MOTS-c

Also known as: Mitochondrial ORF of the 12S rRNA-c

MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial 12S rRNA.

Research context

MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial 12S rRNA. Research characterizes it as a mitochondrial-derived signaling peptide involved in metabolic homeostasis and AMPK pathway modulation. It is studied in insulin-sensitivity models and cellular energetics assays.

Storage & stability

Store lyophilized at -20°C.

Purity & testing standards

Each batch of MOTS-c is analyzed by an independent third-party laboratory. Standard release testing includes reverse-phase HPLC at 220 nm (purity target HPLC ≥98%), electrospray mass spectrometry (identity confirmation), and endotoxin screening. Batch numbers on each vial resolve to a downloadable COA on this site.