GHK-Cu

Also known as: Copper Peptide GHK, Glycyl-Histidyl-Lysine-Cu

GHK-Cu is a naturally occurring tripeptide (glycyl-L-histidyl-L-lysine) that spontaneously forms a stable complex with copper(II) ions.

Research context

GHK-Cu is a naturally occurring tripeptide (glycyl-L-histidyl-L-lysine) that spontaneously forms a stable complex with copper(II) ions. Concentrations of the free tripeptide in human plasma decline with age. In vitro and dermal research applications include extracellular matrix remodeling assays, fibroblast collagen expression studies, and antioxidant enzyme regulation. The copper-bound complex distinguishes GHK-Cu from many peptide reagents by combining a peptide backbone with a redox-active metal center. Supplied as a blue-purple crystalline solid.

Storage & stability

Store lyophilized complex at -20°C. Aqueous solutions should be freshly prepared and used within 14 days.

Purity & testing standards

Each batch of GHK-Cu is analyzed by an independent third-party laboratory. Standard release testing includes reverse-phase HPLC at 220 nm (purity target HPLC ≥99% (peptide portion)), electrospray mass spectrometry (identity confirmation), and endotoxin screening. Batch numbers on each vial resolve to a downloadable COA on this site.